We Are Proudly Gluten-Free, Sulfate-Free, Fluoride-Free, Cruelty-Free, Vegan Clinical Study Clinically Proven Based on a study conducted by University of California, Irvine, Dr. Brite oral care is clinically-proven to better reduce plaque, gum inflammation, and gum bleeding than leading conventional oral care products. Key Ingredients Our star ingredient HYDROXYAPATITE! Hydroxyapatite is a naturally occurring mineral that makes up 97% of our tooth enamel and has been scientifically-proven to whiten, strengthen, and protect your teeth without fluoride. Our oral care features 10% hydroxyapatite that is naturally-derived, vegan, and free of nano particles.