This herbal remedy is often used for both menstruating and pregnant women. The Native Americans used it in the last few weeks of pregnancy to prepare for childbirth.Squaw Vine has been used for menstrual irregularities (amenorrhea, dysmenorrhea, and menorrhagia) and for vaginal discharge (antiseptic properties for vaginal infections). Tones both the uterus and ovaries and helps to relieve congestion. Has a calming effect on the nervous system and may improve digestion. It can be substituted for Pipsissewa. People have used this for: gravel dropsy sore eyes gonorrhea sore nipples urine suppression